Urbanization, mental health, and oral health inequalities in left-behind youth: a systematic review and meta-analysis

Purpose of review This systematic review and meta-analysis evaluated mental and oral health outcomes among left-behind children (LBC) affected by urbanization-driven rural–urban labour migration. Although mental health impacts of parental migration are increasingly recognized, oral health outcomes remain underexplored. This review synthesizes available evidence, quantifies disparities, and identifies shared social and structural determinants. Recent findings […]

Urbanization and mental health in China

Purpose of review The rapid urbanization in China has profoundly transformed social structures, environmental conditions, and public health landscapes within a relatively brief period. While driving economic growth, it has also generated complex mental health challenges. We explored the multifaceted relationships between urbanization and mental health in China, highlighting spatial and demographic disparities, impact pathways, […]

Loneliness and psychosis: an integrative review

Purpose of review This review synthesizes emerging research on loneliness in psychosis, integrating neurocognitive, social, developmental, and phenomenological perspectives. We highlight how loneliness operates as both a precipitant and consequence of psychosis symptoms, discuss its manifestations across the psychosis spectrum, and outline conceptual and clinical priorities for advancing person-centered research and clinical care. Recent findings […]

Urban living and bipolar disorder: a review of the recent evidence

Purpose of review Recent evidence has expanded understanding of how urbanization influences bipolar disorder, yet findings remain inconsistent due in part to heterogeneous definitions of urbanicity. This review synthesizes recent studies using a structured framework encompassing interconnected constructs, timing of exposure, and community-level mechanisms. The aim is to clarify potential mediating factors underlying the relationship […]

JAMA Psychiatry

Mission Statement: JAMA Psychiatry strives to publish original, state-of-the-art studies and commentaries of general interest to clinicians and researchers in psychiatry, mental health, behavioral science, and allied fields. The journal seeks to inform its readers, to stimulate discussion into the nature, causes, treatment, and public health importance of mental illness, and to promote equity and […]

Treatment trials for negative symptoms in schizophrenia

Purpose of review Negative symptoms in schizophrenia remain an unmet treatment need. Recent guidelines and meta-analyses suggest that some pharmacological and psychosocial interventions show modest efficacy. Adding to this evidence, this review summarizes randomized clinical trials (RCTs) published between January 2024 and October 2025 on pharmacological, psychosocial, physical, digital, and neuromodulatory interventions targeting negative symptoms. […]