Error in Abstract
In the Original Investigation titled “Intranasal Oxytocin and Physical Intimacy for Dermatological Wound Healing and Neuroendocrine Stress: A Randomized Clinical Trial,” published online November 12, 2025, there was an error in the Results of the Abstract. The value for the association of greater sexual activity with reduced daily cortisol levels should have been b = −0.083. This […]
Restricting Liafensine on the Basis of ANK3 Genotype—More Evidence Needed
To the Editor A recent study in JAMA Psychiatry reports improvement in treatment-resistant depression with liafensine in patients selected for having genotype GG for the ANK3 intronic variant rs12217173. The authors claim that liafensine failed to demonstrate efficacy in 2 prior large trials in non–biomarker-selected patients and cite 2 publications. However, 1 of these publications […]
Restricting Liafensine on the Basis of ANK3 Genotype—More Evidence Needed—Reply
In Reply We appreciate Curtis’ comments regarding our article published in JAMA Psychiatry. However, we would like to address some possible misunderstandings.
Z-Drug Use in the First Trimester of Pregnancy and Risk of Congenital Malformations
This cohort study evaluates whether exposure to nonbenzodiazepine sedative hypnotics, or Z-drugs, in the first trimester of pregnancy is associated with an increased risk of congenital malformations.
JAMA Psychiatry
Mission Statement: JAMA Psychiatry strives to publish original, state-of-the-art studies and commentaries of general interest to clinicians and researchers in psychiatry, mental health, behavioral science, and allied fields. The journal seeks to inform its readers, to stimulate discussion into the nature, causes, treatment, and public health importance of mental illness, and to promote equity and […]
Why are some cases not on track? An investigation of common obstacles and solutions during feedback-informed psychological therapy.
Journal of Consulting and Clinical Psychology, Vol 94(1), Jan 2026, 1-10; doi:10.1037/ccp0000977 Objectives: Using feedback helps to improve psychological treatment outcomes, particularly for patients whose symptom trajectory is not-on-track. However, little is known about why some cases are not-on-track and what strategies can help to improve their treatment response. This study aimed to examine common […]
Increasing the effectiveness of psychotherapy in routine care through transdiagnostic online modules? Randomized controlled trial investigating blended care.
Journal of Consulting and Clinical Psychology, Vol 94(1), Jan 2026, 11-25; doi:10.1037/ccp0000983 Objective: Blended care (BC), the integration of Internet-based interventions into psychotherapy (PT), is thought of as a promising approach to enhance PT’s effectiveness and efficiency. This randomized controlled trial aimed to investigate the effectiveness as well as the implementation and usage of BC […]
What works for whom in outpatient cognitive-behavioral therapy? Integration of techniques from different therapeutic orientations and their interactions as predictors of treatment outcome in different diagnostic groups.
Journal of Consulting and Clinical Psychology, Vol 94(1), Jan 2026, 26-38; doi:10.1037/ccp0000987 Objective: The mechanisms underlying psychotherapy’s effects remain debated, with some emphasizing theory-specific therapeutic techniques and others highlighting common factors like therapeutic alliance. Evidence is inconclusive partially because it is rarely assessed which interventions are actually employed in naturalistic outpatient settings. The study thus […]
Strengthening couple functioning to enhance child outcomes in low-income families: A randomized controlled trial.
Journal of Consulting and Clinical Psychology, Vol 94(1), Jan 2026, 39-48; doi:10.1037/ccp0000988 Objective: Large-scale efforts have disseminated couple and relationship programs to strengthen couple relationships among low-income families, with the hope that doing so would yield benefits for partners and their children. The present study provided a rigorous test of this hypothesis by examining indirect […]
Who benefits most from couple relationship education: A machine learning approach.
Journal of Consulting and Clinical Psychology, Vol 94(1), Jan 2026, 49-62; doi:10.1037/ccp0000991 Objective: Couple relationship education (CRE) seeks to enhance relationship functioning and prevent deterioration of relationship quality over time. However, impacts of CRE are mixed and often appear to be influenced by the characteristics of the couples receiving the intervention. To provide effective interventions, […]