Apathy in dementia: pharmacological and nonpharmacological treatment strategies

Purpose of review Apathy is one of the most prevalent and disabling symptoms of neurodegenerative disorders, yet targeted treatments remain poorly defined. In recent years, growing interest in its conceptualization and management has led to an increasing number of randomized controlled trials (RCTs) and meta-analyses addressing both pharmacological and nonpharmacological interventions. Recent findings Among pharmacological […]

The impact of routine outcome monitoring and feedback integration on treatment outcome: A therapist-specific indicator of belief updating processes?

Journal of Consulting and Clinical Psychology, Vol 93(12), Dec 2025, 804-813; doi:10.1037/ccp0000974 Objectives: Therapists vary widely in their use of feedback, which may reflect differences in how they incorporate feedback into their clinical judgment—especially when their evaluations diverge from their patients’. This process, often referred to as belief updating, involves adapting one’s perspective based on […]

Questioning the distinction between active elements and mechanisms: Evidence from a reanalysis in cognitive behavioral therapy of depression.

Journal of Consulting and Clinical Psychology, Vol 93(12), Dec 2025, 829-834; doi:10.1037/ccp0000984 Objective: A new theoretical measurement framework for assessing active elements in cognitive behavioral therapies (CBT) emphasizes distinguishing various aspects of therapeutic components, and differentiating processes occurring within and between sessions. In this article, we apply the framework to data analyzed prior to its […]

Emotion regulation as a transdiagnostic treatment construct across group cognitive behavioral therapies for adult anxiety and depression.

Journal of Consulting and Clinical Psychology, Vol 93(12), Dec 2025, 789-803; doi:10.1037/ccp0000967 Objectives: Identifying the mechanisms of change in first-line cognitive behavioral therapy (CBT) protocols for adult anxiety and depression could enhance outcomes for the individual. We explored (a) the effect of four group CBT protocols on general emotion regulation skills, (b) the effect of […]

Is there a treatment for the Turker blues? A fully remote nationwide randomized controlled trial of a digital intervention for depression in adult online workers.

Journal of Consulting and Clinical Psychology, Vol 93(11), Nov 2025, 719-734; doi:10.1037/ccp0000982 Objective: We conducted a nationwide, fully remote two-arm randomized controlled trial to test the efficacy of a self-guided internet-based behavioral activation (BA) intervention for depression in online workers. The intervention was a 4-week program designed as part of the Common Element Toolbox (COMET). […]

Between- and within-person relations between treatment modules and symptom improvements across six randomized controlled trials.

Journal of Consulting and Clinical Psychology, Vol 93(11), Nov 2025, 735-748; doi:10.1037/ccp0000972 Objective: Most youth psychotherapies contain multiple treatment elements; little is known about their relative effectiveness. We assessed symptom improvements associated with treatment elements, represented by modules within modular psychotherapy. Method: Data from six clinical trials of the modular approach to therapy for children […]

Dynamic and dyadic relationships between facial behavior, working alliance, and treatment outcomes during depression therapy.

Journal of Consulting and Clinical Psychology, Vol 93(11), Nov 2025, 749-760; doi:10.1037/ccp0000980 Objective: Previous work has yielded mixed results regarding the relationships of interpersonal synchrony with working alliance and treatment outcomes. We sought to clarify these relationships by applying more sophisticated dynamic and dyadic methods. Method: Adult outpatients with depression (N = 65, age 18–64, […]

Dynamic prediction of inpatient self-harm and suicide attempts using machine learning: Toward data-driven clinical monitoring.

Journal of Consulting and Clinical Psychology, Vol 93(11), Nov 2025, 761-776; doi:10.1037/ccp0000971 Objective: Self-harm and suicide attempts are notoriously difficult to predict and to prevent, particularly as they are low base-rate events. This study aimed to improve prediction by combining static information—unchanging patient characteristics collected at admission—with dynamic self-reported mental health data collected daily during […]

JAMA Psychiatry

Mission Statement: JAMA Psychiatry strives to publish original, state-of-the-art studies and commentaries of general interest to clinicians and researchers in psychiatry, mental health, behavioral science, and allied fields. The journal seeks to inform its readers, to stimulate discussion into the nature, causes, treatment, and public health importance of mental illness, and to promote equity and […]