Structural Drivers of the Drop in Opioid Overdose Deaths in the US
This decision analytical model uses the SOURCE model to elucidate factors underlying the recent decline in US overdose deaths.
A Genetic Risk Adoption Design for Psychiatric and Substance Use Disorders
This cohort study evaluates associations among paternal family genetic risk scores and key psychiatric disorders.
Telemental Health, Hybrid, and In-Person Outpatient Mental Health Care in the US
This cross-sectional study evaluates sociodemographic and clinical characteristics in telehealth, hybrid, and in-person mental health care.
Uptake, Adherence, and Attrition in Clinical Trials of Depression and Anxiety Apps
This systematic review and meta-analysis examines data from randomized clinical trials of apps for managing depression and anxiety to determine rates of app uptake, posttest and follow-up attrition, and adherence.
Treatment trials for negative symptoms in schizophrenia
Purpose of review Negative symptoms in schizophrenia remain an unmet treatment need. Recent guidelines and meta-analyses suggest that some pharmacological and psychosocial interventions show modest efficacy. Adding to this evidence, this review summarizes randomized clinical trials (RCTs) published between January 2024 and October 2025 on pharmacological, psychosocial, physical, digital, and neuromodulatory interventions targeting negative symptoms. […]
Childhood adversities and the exposome in dementia risk and brain health
Purpose of review Prevention research has largely concentrated on mid- and late-life modifiable risk factors, whereas early-life adversities have received less attention. Growing evidence shows that early adversities can influence brain health across biological systems and social environments, yet findings are fragmented and rarely address broader structural conditions. This review synthesizes recent evidence and introduces […]
The long-term effectiveness of psychodynamic and analytical psychotherapy in routine care: Results from a naturalistic study over 6 years.
Journal of Consulting and Clinical Psychology, Vol 93(12), Dec 2025, 814-828; doi:10.1037/ccp0000985 Objective: This naturalistic study examines the long-term effectiveness of two psychoanalytically oriented therapies—psychodynamic psychotherapy (PP) and analytical psychotherapy (AP)—in routine care settings in Germany. Method: A total of 428 patients diagnosed with various mental disorders according to the Diagnostic and Statistical Manual of […]
Error in Abstract
In the Original Investigation titled “Pragmatic Comparative Effectiveness of Primary Care Treatments for Posttraumatic Stress Disorder: a Randomized Clinical Trial,” published online October 15, 2025, there was an error in the Results of the Abstract. The phrase “11 of 352 patients (31.5%) randomized to WET” was changed to “111 of 352 patients (31.5%) randomized to […]
Age-only versus multivariable models for dementia prediction: a comparative analysis
Purpose of review Accurate dementia risk prediction is critical for prevention, yet it remains unclear which predictors add meaningful value beyond chronological age. This review evaluates the extent to which multivariable dementia risk models identify modifiable risk factors that enhance prediction value. Recent findings We systematically reviewed cohort studies reporting both age-only and multivariable dementia […]
Climate change and dementia: the impacts of social inequalities
Purpose of review Climate change has emerged as a critical global health challenge, which poses significant risks to brain health and well being among older adults. This review summarized the evidence from the past 2 years on how climate change shapes cognitive health and further explored how social inequities amplify the climate-related exposures and the […]